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N-OMEGA-PROPYL-L-ARGININE

Product Name
N-OMEGA-PROPYL-L-ARGININE
CAS No.
137361-05-8
Chemical Name
N-OMEGA-PROPYL-L-ARGININE
Synonyms
N-PLA;NΩZinc01546170;N-alpha,Nω-dimethyl-Nω-PROPYL-L-ARGININE;-bis-Boc-D-arginine;NW-PROPYL-L-ARGININE;NG-PROPYL-L-ARGININE;Nω-Propyl-L-Arginine
CBNumber
CB3410297
Molecular Formula
C9H20N4O2
Formula Weight
216.28
MOL File
137361-05-8.mol
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N-OMEGA-PROPYL-L-ARGININE Property

Melting point:
198-200?C
Boiling point:
366.5±52.0 °C(Predicted)
Density 
1.24±0.1 g/cm3(Predicted)
storage temp. 
Desiccate at RT
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
2.50±0.24(Predicted)
form 
White to off-white solid.
color 
White
Stability:
Very Hygroscopic
CAS DataBase Reference
137361-05-8(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2341
Product name
Nω-Propyl-L-Arginine hydrochloride
Purity
≥98% (HPLC)
Packaging
5mg
Price
$94.2
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2341
Product name
Nω-Propyl-L-Arginine hydrochloride
Purity
≥98% (HPLC)
Packaging
25mg
Price
$306
Updated
2024/03/01
Cayman Chemical
Product number
80587
Product name
Nω-propyl-L-Arginine
Purity
≥98%
Packaging
5mg
Price
$55
Updated
2024/03/01
Cayman Chemical
Product number
80587
Product name
Nω-propyl-L-Arginine
Purity
≥98%
Packaging
10mg
Price
$101
Updated
2024/03/01
Cayman Chemical
Product number
80587
Product name
Nω-propyl-L-Arginine
Purity
≥98%
Packaging
50mg
Price
$420
Updated
2024/03/01
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N-OMEGA-PROPYL-L-ARGININE Chemical Properties,Usage,Production

Description

Nω-Propyl-L-Arginine is a potent and selective inhibitor of neuronal nitric oxide synthase (nNOS). Nω-Propyl-L-Arginine is a competitive inhibitor of bovine nNOS having a Ki value of 57 nM. The Ki values for eNOS (bovine) and iNOS (murine) are 8.5 and 180 μM, respectively. Nω-propyl-L-Arginine therefore exhibits 3,000-fold and 150-fold selectivity for the neuronal isoform versus the inducible (murine) and endothelial (bovine) isoforms of NOS, respectively.

Chemical Properties

Off-White Solid

Uses

Nω-Propyl-L-Arginine is a neuronal selective nitric oxide synthase inhibitor (1) and a highly selective competitive inhibitor and inactivator of all three isoforms of NOS (2,3).

Uses

A highly selective competitive inhibitor and inactivator of all three isoforms of NOS.

Biological Activity

Highly selective and potent inhibitor of nNOS (K i = 57 nM). Displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Hypotensive in vivo .

storage

room temperature (desiccate)

N-OMEGA-PROPYL-L-ARGININE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-OMEGA-PROPYL-L-ARGININE Suppliers

Canada 1 China 36 Europe 1 Germany 3 India 1 Switzerland 1 United Kingdom 6 United States 14 USA 1 Global 64
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8449
Advantage
60
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63711
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52927
Advantage
58

137361-05-8, N-OMEGA-PROPYL-L-ARGININERelated Search:

N-ACETYLLACTOSAMINE Dodecyl acrylate L-Ornithine Nomega-Propyl-L-arginine BRADYKININ DIACETATE HEPTAHYDRATE ARGININOSUCCINIC ACID DISODIUM SALT

  • L-N5-(1-IMINO-9-PROPYLAMINO-O-METHYL)ORINTHINE
  • L-N5-(1-IMINO(PROPYLAMINO))METHYL-ORNITHINE
  • 2(S)-2-AMINO-5-(N-PROPYLGUANIDINO)PENTANOIC ACID
  • N5-[IMINO(PROPYLAMINO)METHYL]-L-ORNITHINE
  • NW-PROPYL-L-ARGININE
  • N-PLA
  • N-OMEGA-PROPYL-L-ARGININE
  • NG-PROPYL-L-ARGININE
  • N&OMEGA
  • -PROPYL-L-ARGININE
  • N-2-PROPYL-L-ARGININE
  • Zinc01546170
  • N5-[Imino(propylamino)methyl]-L-ornithinehydrochloride
  • Nω-Propyl-L-arginine hydrochloride
  • N5-[IMino(propylaMino)Methyl]-
  • -Propyl-L-arginine hydrochloride
  • Nω-Propyl-L-Arginine
  • -Hydroxy-nor-L-Arginine Dihydrochloride
  • -Methyl-L-arginine hydrochloride
  • -bis-Z-L-arginine N-hydroxysuccinimide ester
  • -bis-Boc-D-arginine
  • N-alpha,N&omega
  • -Tris-Z-L-arginine N-hydroxysuccinimide ester
  • -(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-D-arginine
  • -(di-tert-butyloxycarbonyl)-L-arginine cyclohexylammonium salt
  • -(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine tert-butyl ester
  • -(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine
  • -dimethyl-N&omega
  • -Hydroxy-L-arginine monoacetate
  • -(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-D-arginine-2-chlorotrityl resin
  • (S)-2-Amino-5-(3-propylguanidino)pentanoic acid
  • -Nitro-D-arginine methyl ester hydrochloride
  • -(2,2,4,6,7-Pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine methyl ester hydrochloride
  • -(2,2,4,6,7-Pentamethyldihydro-benzofuran-5-sulfonyl)-L-arginine allyl ester hydrochloride
  • L-Ornithine, N5-[imino(propylamino)methyl]-
  • Nomega-Propyl-L-arginine hydrochloride
  • 137361-05-8
  • C9H20N4O2
  • C9H20N4O2HCl
  • All Inhibitors
  • Inhibitors
  • Nitric Oxide Reagents
  • Amino Acids & Derivatives